Disorders of lacrimal system

H7_LACRIMALSYSTEM

lacrimal apparatus disease: A non-neoplastic or neoplastic disorder that affects the lacrimal apparatus. [ NCIT:C26809 ]

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H04
Cause of death: ICD-10 H04

2 out of 7 registries used, show all original rules.

14937

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Check minimum number of events None

14937

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Remove individuals based on genotype QC

14748

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H7_LACRIMALSYSTEM

Control definitions

Control exclude H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H00-H06
Name in latin Morbositates apparati lacrimalis

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 14748 10621 4127
Unadjusted prevalence (%) 3.58 4.61 2.27
Mean age at first event (years) 56.10 55.01 58.91

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.02 [1.53, 2.67] 6.8e-7 1122
15 years 0.01 1.28 [1.03, 1.60] 2.9e-2 515
5 years 0.00 2.54 [2.09, 3.09] 1.7e-20 356
1 year 0.00 3.62 [2.80, 4.69] 8.9e-23 99

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_LACRIMALSYSTEM – Disorders of lacrimal system
GWS hits: 1

Survival analyses between endpoints

Plot

before Disorders of lacrimal system
after Disorders of lacrimal system

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Drugs most likely to be purchased after Disorders of lacrimal system

Endpoint not on priority list, no data to show.