Keratitis

H7_KERATITIS

keratitis: Inflammation of the cornea. [ NCIT:P378 ]

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H16, H17, H18, H19*
Cause of death: ICD-10 H16, H17, H18, H19*

2 out of 7 registries used, show all original rules.

13069

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Check minimum number of events None

13069

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Remove individuals based on genotype QC

12916

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H7_KERATITIS

Control definitions

Control exclude H7_SCLERACORNEA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 12916 7138 5778
Unadjusted prevalence (%) 3.14 3.10 3.18
Mean age at first event (years) 50.41 49.60 51.42

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.71 [2.21, 3.33] 1.7e-21 1077
15 years 0.01 1.70 [1.43, 2.02] 1.5e-9 482
5 years 0.00 2.84 [2.41, 3.35] 4.5e-35 303
1 year 0.00 4.96 [3.93, 6.26] 2.5e-41 108

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_KERATITIS – Keratitis
GWS hits: 9

Survival analyses between endpoints

Plot

before Keratitis
after Keratitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Keratitis

Endpoint not on priority list, no data to show.