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Keratitis

DOID EFO MESH SNOMED Endpoint Browser PheWeb

H7_KERATITIS

keratitis: Inflammation of the cornea. [ NCIT:P378 ]

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H16, H17, H18, H19*
Cause of death: ICD-10 H16, H17, H18, H19*

2 out of 7 registries used, show all original rules.

13069

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Check minimum number of events None

13069

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Include endpoints

13401

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Remove individuals based on genotype QC

12916

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H7_KERATITIS

Control definitions

Control exclude H7_SCLERACORNEA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 12916 7138 5778
Unadjusted prevalence (%) 3.14 3.10 3.18
Mean age at first event (years) 50.41 49.60 51.42

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.71 [2.21, 3.33] 1.7e-21 1077
15 years 0.01 1.70 [1.43, 2.02] 1.5e-9 482
5 years 0.00 2.84 [2.41, 3.35] 4.5e-35 303
1 year 0.00 4.96 [3.93, 6.26] 2.5e-41 108

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_KERATITIS – Keratitis
GWS hits: 9

Survival analyses between endpoints

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Plot

before Keratitis
after Keratitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Keratitis

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Endpoint not on priority list, no data to show.