Other disorders of eye and adnexa

DOID EFO MESH SNOMED Endpoint Browser PheWeb

H7_EYEOTH

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

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FinnGen phenotype data

429209 individuals

Apply sex-specific rule None

429209

Check conditions None

429209

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H55-H59

Cause of death: ICD-10 H55-H59

2 out of 7 registries used, show all original rules.

4375

Check minimum number of events None

4375

Include endpoints

H7_NYSTAGMUS

H7_ANOMAPUPFUNC

H7_OCUPAIN

H7_EYEADNEXOTH

H7_OTHEREYEINOTH

4604

Remove individuals based on genotype QC

4406

H7_EYEOTH

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

NAME	H7_EYEOTH
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	H7_NYSTAGMUS\|H7_ANOMAPUPFUNC\|H7_OCUPAIN\|H7_EYEADNEXOTH\|H7_OTHEREYEINOTH
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H5[5-9]
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H5[5-9]
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Other disorders of eye and adnexa based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	4406	3002	1404
Unadjusted prevalence (%)	1.07	1.30	0.77
Mean age at first event (years)	48.75	48.07	50.21

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	1.68 [1.14, 2.48]	8.9e-3	326
15 years	0.01	0.98 [0.67, 1.44]	9.2e-1	136
5 years	0.00	2.06 [1.48, 2.87]	1.8e-5	93
1 year	0.00	3.50 [2.25, 5.45]	3.0e-8	30

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_EYEOTH – Other disorders of eye and adnexa
GWS hits: 2

Survival analyses between endpoints

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Plot

before Other disorders of eye and adnexa
after Other disorders of eye and adnexa

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Table

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Drugs most likely to be purchased after Other disorders of eye and adnexa

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Endpoint not on priority list, no data to show.

≡ Risteys

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