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conjunctival degenerations and deposits

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H7_CONJUNCTDEGDEPOT

pinguecula: A yellowish thickened lesion on the conjunctiva near the cornea representing a benign degenerative change in the conjunctiva caused by the leakage and deposition of certain blood proteins through the permeable capillaries near the limbus.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H11.1
Hospital discharge: ICD-9 3725
Cause of death: ICD-10 H11.1
Cause of death: ICD-9 3725

2 out of 7 registries used, show all original rules.

642

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Check minimum number of events None

642

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Include endpoints None

642

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Remove individuals based on genotype QC

613

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H7_CONJUNCTDEGDEPOT

Control definitions

Control exclude H7_CONJUNCTIVA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H11
Name in latin Degenerationes et deposita conjunctivae

Summary Statistics

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Key figures

All Female Male
Number of individuals 613 389 224
Unadjusted prevalence (%) 0.15 0.17 0.12
Mean age at first event (years) 52.57 50.56 56.07

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.29 [0.49, 3.42] 6.1e-1 79
15 years 0.01 1.05 [0.53, 2.09] 8.8e-1 36
5 years 0.00 1.10 [0.50, 2.40] 8.2e-1 10
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_CONJUNCTDEGDEPOT – conjunctival degenerations and deposits
GWS hits:

Survival analyses between endpoints

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Plot

before conjunctival degenerations and deposits
after conjunctival degenerations and deposits

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after conjunctival degenerations and deposits

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Endpoint not on priority list, no data to show.