Chorioretinal inflammation

H7_CHORIORETINFLAM

pars planitis: Form of granulomatous uveitis occurring in the region of the pars plana. This disorder is a common condition with no detectable focal pathology. It causes fibrovascular proliferation at the inferior ora serrata.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H30, H32.0*, H32.0*A18.5, H32.0*A52.79, H32.0*A69.2, H32.0*B58.0
Hospital discharge: ICD-9 363[0-2]
Hospital discharge: ICD-8 365|36700
Cause of death: ICD-9 363[0-2]
Cause of death: ICD-8 365|36700

2 out of 7 registries used, show all original rules.

859

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Check minimum number of events None

859

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Include endpoints None

859

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Remove individuals based on genotype QC

835

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H7_CHORIORETINFLAM

Control definitions

Control exclude H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF6

Summary Statistics

Key figures

All Female Male
Number of individuals 835 485 350
Unadjusted prevalence (%) 0.20 0.21 0.19
Mean age at first event (years) 45.94 44.20 48.35

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.11 5.81 [3.79, 8.89] 5.4e-16 82
15 years 0.02 2.75 [1.69, 4.48] 4.9e-5 30
5 years 0.01 5.67 [3.43, 9.37] 1.2e-11 22
1 year 0.00 17.63 [9.70, 32.05] 4.9e-21 14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_CHORIORETINFLAM – Chorioretinal inflammation
GWS hits:

Survival analyses between endpoints

Plot

before Chorioretinal inflammation
after Chorioretinal inflammation

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Chorioretinal inflammation

Endpoint not on priority list, no data to show.