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Other cataract

DOID EFO MESH SNOMED Endpoint Browser PheWeb

H7_CATARACTOTHER

cataract: Partial or complete opacity of the crystalline lens of one or both eyes that decreases visual acuity and eventually results in blindness. Some cataracts appear in infancy or in childhood, but most develop in older individuals. (Sternberg Diagnostic Surgical Pathology, 3rd ed.)

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H26
Hospital discharge: ICD-9 366
Hospital discharge: ICD-8 374
Hospital discharge: excluded ICD-9 3661
Hospital discharge: excluded ICD-8 37403
Cause of death: ICD-10 H26
Cause of death: ICD-9 366
Cause of death: ICD-8 374
Cause of death: excluded ICD-9 3661
Cause of death: excluded ICD-8 37403

2 out of 7 registries used, show all original rules.

20030

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Check minimum number of events None

20030

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Include endpoints None

20030

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Remove individuals based on genotype QC

19401

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H7_CATARACTOTHER

Control definitions

Control exclude H7_LENS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H25-H28
Name in latin Alia cataracta

Summary Statistics

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Key figures

All Female Male
Number of individuals 19401 11111 8290
Unadjusted prevalence (%) 4.71 4.83 4.56
Mean age at first event (years) 66.85 67.39 66.13

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.02 [1.70, 2.41] 2.4e-15 3453
15 years 0.01 1.39 [1.23, 1.58] 3.6e-7 1591
5 years 0.00 2.44 [2.19, 2.71] 7.9e-61 1159
1 year 0.00 2.86 [2.45, 3.34] 2.2e-40 280

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_CATARACTOTHER – Other cataract
GWS hits: 14

Survival analyses between endpoints

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Plot

before Other cataract
after Other cataract

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Drugs most likely to be purchased after Other cataract

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Endpoint not on priority list, no data to show.