Gestational diabetes (for exclusion)

GEST_DIABETES

cerebrovascular disorder: A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule

Sex only females

239906

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Check conditions None

239906

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 O24.4
Hospital discharge: ICD-9 6488A
Cause of death: ICD-10 O24.4
Cause of death: ICD-9 6488A

2 out of 7 registries used, show all original rules.

15525

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Check minimum number of events None

15525

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Include endpoints None

15525

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Remove individuals based on genotype QC

14718

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GEST_DIABETES

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF4
Parent code in ICD-10 O24
Name in latin Diabetes mellitus in gravidate apparens

Summary Statistics

Key figures

All Female Male
Number of individuals 14718 14718 -
Unadjusted prevalence (%) 3.57 6.39 -
Mean age at first event (years) 31.79 31.79 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.28 [0.94, 1.74] 1.2e-1 106
15 years 0.01 0.77 [0.50, 1.19] 2.4e-1 27
5 years 0.00 1.64 [0.90, 3.00] 1.1e-1 12
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: GEST_DIABETES – Gestational diabetes (for exclusion)
GWS hits: 17

Survival analyses between endpoints

Plot

before Gestational diabetes (for exclusion)
after Gestational diabetes (for exclusion)

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Drugs most likely to be purchased after Gestational diabetes (for exclusion)

Endpoint not on priority list, no data to show.