Status epilepticus

G6_STATUSEPI

status epilepticus: Status epilepticus is defined as a continuous seizure lasting more than 30 min, or two or more seizures without full recovery of consciousness between any of them.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G41
Hospital discharge: ICD-9 3452|3453
Hospital discharge: ICD-8 34520
Cause of death: ICD-10 G41
Cause of death: ICD-9 3452|3453
Cause of death: ICD-8 34520

2 out of 7 registries used, show all original rules.

1170

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Check minimum number of events None

1170

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Include endpoints None

1170

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Remove individuals based on genotype QC

1121

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G6_STATUSEPI

Control definitions

Control exclude G6_EPIPAROX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G40-G47
Name in latin Status epilepticus

Summary Statistics

Key figures

All Female Male
Number of individuals 1121 501 620
Unadjusted prevalence (%) 0.27 0.22 0.34
Mean age at first event (years) 53.81 49.69 57.14

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.21 10.99 [5.60, 21.58] 3.3e-12 385
15 years 0.03 3.66 [2.21, 6.06] 4.7e-7 85
5 years 0.01 10.30 [7.25, 14.63] 8.1e-39 98
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_STATUSEPI – Status epilepticus
GWS hits: 1

Survival analyses between endpoints

Plot

before Status epilepticus
after Status epilepticus

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Status epilepticus

Endpoint not on priority list, no data to show.