Other demyelinating diseases of the central nervous system

G6_OTHDEMYEL

No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G37
Hospital discharge: ICD-9 341[1-9]
Hospital discharge: ICD-8 3410[2-9]
Cause of death: ICD-10 G37
Cause of death: ICD-9 341[1-9]
Cause of death: ICD-8 3410[2-9]

2 out of 7 registries used, show all original rules.

1191

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Check minimum number of events None

1191

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Include endpoints None

1191

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Remove individuals based on genotype QC

1149

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G6_OTHDEMYEL

Control definitions

Control exclude G6_DEMYEL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G35-G37
Name in latin Alii morbi demyelinantes systematis nervosi centralis

Summary Statistics

Key figures

All Female Male
Number of individuals 1149 845 304
Unadjusted prevalence (%) 0.28 0.37 0.17
Mean age at first event (years) 40.37 39.40 43.08

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 4.85 [2.58, 9.12] 9.6e-7 46
15 years 0.01 1.29 [0.53, 3.16] 5.8e-1 10
5 years 0.01 5.18 [2.58, 10.38] 3.5e-6 13
1 year 0.01 21.28 [9.99, 45.34] 2.3e-15 11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_OTHDEMYEL – Other demyelinating diseases of the central nervous system
GWS hits: 1

Survival analyses between endpoints

Plot

before Other demyelinating diseases of the central nervous system
after Other demyelinating diseases of the central nervous system

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Drugs most likely to be purchased after Other demyelinating diseases of the central nervous system

Endpoint not on priority list, no data to show.