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Monoplegia

DOID EFO MESH SNOMED Endpoint Browser PheWeb

G6_MONOPLE

cycloplegia: Cycloplegia is paralysis of the ciliary muscle of the eye, resulting in a loss of accommodation.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G83.1, G83.2, G83.3
Cause of death: ICD-10 G83.1, G83.2, G83.3

2 out of 7 registries used, show all original rules.

429

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Check minimum number of events None

429

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Include endpoints None

429

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Remove individuals based on genotype QC

415

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G6_MONOPLE

Control definitions

Control exclude G6_CPETAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 415 237 178
Unadjusted prevalence (%) 0.10 0.10 0.10
Mean age at first event (years) 55.56 52.47 59.66

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 4.88 [1.94, 12.28] 7.8e-4 76
15 years 0.02 2.32 [1.06, 5.06] 3.5e-2 26
5 years 0.01 5.53 [2.86, 10.70] 3.8e-7 27
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_MONOPLE – Monoplegia
GWS hits:

Survival analyses between endpoints

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Plot

before Monoplegia
after Monoplegia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Monoplegia

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Endpoint not on priority list, no data to show.