Monoplegia

G6_MONOPLE

cycloplegia: Cycloplegia is paralysis of the ciliary muscle of the eye, resulting in a loss of accommodation.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G83.1, G83.2, G83.3
Cause of death: ICD-10 G83.1, G83.2, G83.3

2 out of 7 registries used, show all original rules.

429

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Check minimum number of events None

429

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Include endpoints None

429

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Remove individuals based on genotype QC

415

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G6_MONOPLE

Control definitions

Control exclude G6_CPETAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 415 237 178
Unadjusted prevalence (%) 0.10 0.10 0.10
Mean age at first event (years) 55.56 52.47 59.66

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 4.88 [1.94, 12.28] 7.8e-4 76
15 years 0.02 2.32 [1.06, 5.06] 3.5e-2 26
5 years 0.01 5.53 [2.86, 10.70] 3.8e-7 27
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_MONOPLE – Monoplegia
GWS hits:

Survival analyses between endpoints

Plot

before Monoplegia
after Monoplegia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Monoplegia

Endpoint not on priority list, no data to show.