Bacterial meningitis

DOID EFO MESH SNOMED Endpoint Browser PheWeb

G6_MENINGBACT

bacterial meningitis: Inflammation of the membranes surrounding the brain and spinal cord due to a bacterial infection.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G0[0-1]

Hospital discharge: ICD-9 320

Hospital discharge: ICD-8 320

Cause of death: ICD-10 G0[0-1]

Cause of death: ICD-9 320

Cause of death: ICD-8 320

2 out of 7 registries used, show all original rules.

1087

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Check minimum number of events None

1087

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Include endpoints None

1087

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Remove individuals based on genotype QC

1055

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G6_MENINGBACT

Control definitions

Control exclude G6_NEUINFL

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

NAME	G6_MENINGBACT
CONTROL_EXCLUDE	G6_NEUINFL
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	G0[0-1]
HD_ICD_9	320
HD_ICD_8	320
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	G0[0-1]
COD_ICD_9	320
COD_ICD_8	320
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Bacterial meningitis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1055	547	508
Unadjusted prevalence (%)	0.26	0.24	0.28
Mean age at first event (years)	32.20	30.87	33.64

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	2.96 [1.27, 6.90]	1.2e-2	112
15 years	0.01	1.67 [0.88, 3.16]	1.2e-1	34
5 years	0.00	1.87 [0.91, 3.84]	8.7e-2	13
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_MENINGBACT – Bacterial meningitis
GWS hits:

Survival analyses between endpoints

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Plot

before Bacterial meningitis
after Bacterial meningitis

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Table

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Drugs most likely to be purchased after Bacterial meningitis

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Endpoint not on priority list, no data to show.