Bacterial meningitis

G6_MENINGBACT

bacterial meningitis: Inflammation of the membranes surrounding the brain and spinal cord due to a bacterial infection.

Endpoint definition

FinnGen phenotype data

429209 individuals

diagram downward connector

Apply sex-specific rule None

429209

diagram downward connector

Check conditions None

429209

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G0[0-1]
Hospital discharge: ICD-9 320
Hospital discharge: ICD-8 320
Cause of death: ICD-10 G0[0-1]
Cause of death: ICD-9 320
Cause of death: ICD-8 320

2 out of 7 registries used, show all original rules.

1087

diagram downward connector

Check minimum number of events None

1087

diagram downward connector

Include endpoints None

1087

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

1055

diagram downward connector
G6_MENINGBACT

Control definitions

Control exclude G6_NEUINFL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1055 547 508
Unadjusted prevalence (%) 0.26 0.24 0.28
Mean age at first event (years) 32.20 30.87 33.64

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 2.96 [1.27, 6.90] 1.2e-2 112
15 years 0.01 1.67 [0.88, 3.16] 1.2e-1 34
5 years 0.00 1.87 [0.91, 3.84] 8.7e-2 13
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_MENINGBACT – Bacterial meningitis
GWS hits:

Survival analyses between endpoints

Plot

before Bacterial meningitis
after Bacterial meningitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Bacterial meningitis

Endpoint not on priority list, no data to show.