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Hemiplegia

DOID EFO MESH SNOMED Endpoint Browser PheWeb

G6_HEMIPLE

hemiplegia: Severe or complete loss of motor function on one side of the body. This condition is usually caused by brain diseases that are localized to the cerebral hemisphere opposite to the side of weakness. Less frequently, brain stem lesions; cervical spinal cord diseases; peripheral nervous system diseases; and other conditions may manifest as hemiplegia. The term hemiparesis (see paresis) refers to mild to moderate weakness involving one side of the body. [ MESH:D006429 ]

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G81
Hospital discharge: ICD-9 342
Hospital discharge: ICD-8 34400
Cause of death: ICD-10 G81
Cause of death: ICD-9 342
Cause of death: ICD-8 34400

2 out of 7 registries used, show all original rules.

1740

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Check minimum number of events None

1740

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Include endpoints None

1740

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Remove individuals based on genotype QC

1673

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G6_HEMIPLE

Control definitions

Control exclude G6_CPETAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G80-G83
Name in latin Hemiplegia

Summary Statistics

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Key figures

All Female Male
Number of individuals 1673 866 807
Unadjusted prevalence (%) 0.41 0.38 0.44
Mean age at first event (years) 51.65 46.87 56.77

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.23 [2.04, 5.12] 5.7e-7 445
15 years 0.01 1.85 [1.36, 2.50] 7.4e-5 161
5 years 0.01 3.58 [2.80, 4.57] 2.1e-24 117
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_HEMIPLE – Hemiplegia
GWS hits: 1

Survival analyses between endpoints

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Plot

before Hemiplegia
after Hemiplegia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hemiplegia

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Endpoint not on priority list, no data to show.