Senile degeneration of the brain, not elsewhere classified

G6_DEGENSEN

neurodegenerative disease: A disorder of the central nervous system characterized by gradual and progressive loss of neural tissue and neurologic function.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G31.1
Hospital discharge: ICD-9 3312
Hospital discharge: ICD-8 34792
Cause of death: ICD-10 G31.1
Cause of death: ICD-9 3312
Cause of death: ICD-8 34792

2 out of 7 registries used, show all original rules.

126

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Check minimum number of events None

126

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Include endpoints None

126

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Remove individuals based on genotype QC

120

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G6_DEGENSEN

Control definitions

Control exclude G6_NEURODEG

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF6
Parent code in ICD-10 G31
Name in latin Degeneratio cerebri senilis non alibi classificata

Summary Statistics

Key figures

All Female Male
Number of individuals 120 41 79
Unadjusted prevalence (%) 0.03 0.02 0.04
Mean age at first event (years) 71.64 70.15 72.41

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_DEGENSEN – Senile degeneration of the brain, not elsewhere classified
GWS hits:

Survival analyses between endpoints

Plot

before Senile degeneration of the brain, not elsewhere classified
after Senile degeneration of the brain, not elsewhere classified

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Drugs most likely to be purchased after Senile degeneration of the brain, not elsewhere classified

Endpoint not on priority list, no data to show.