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This is a non-core endpoint: only basic statistics are computed.

Congenital and developmental myasthenia

G6_CONDEVMYA

Myasthenia gravis: Myasthenia gravis (MG) is a rare, clinically heterogeneous, autoimmune disorder of the neuromuscular junction characterized by fatigable weakness of voluntary muscles.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G70.20, G70.21, G70.28
Cause of death: ICD-10 G70.20, G70.21, G70.28

2 out of 7 registries used, show all original rules.

31

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Check minimum number of events None

31

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Include endpoints None

31

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Remove individuals based on genotype QC

29

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G6_CONDEVMYA

Control definitions

Control exclude G6_MYONEU

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 29 19 10
Unadjusted prevalence (%) 0.01 0.01 0.01
Mean age at first event (years) 49.38 41.86 63.67

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: G6_CONDEVMYA – Congenital and developmental myasthenia
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Congenital and developmental myasthenia

Endpoint not on priority list, no data to show.