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Generalized anxiety disorder

DOID EFO MESH SNOMED Endpoint Browser PheWeb

F5_GAD

generalized anxiety disorder: An anxiety disorder that is characterized by long-lasting anxiety that is not focused on any one object or situation.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F41.1
Hospital discharge: ICD-9 3000C
Cause of death: ICD-10 F41.1
Cause of death: ICD-9 3000C

2 out of 7 registries used, show all original rules.

5478

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Check minimum number of events None

5478

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Include endpoints None

5478

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Remove individuals based on genotype QC

5279

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F5_GAD

Control definitions

Control exclude F5_NEUROTIC

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F41
Name in latin Perturbatio anxifera generalisata

Summary Statistics

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Key figures

All Female Male
Number of individuals 5279 3845 1434
Unadjusted prevalence (%) 1.28 1.67 0.79
Mean age at first event (years) 40.11 39.54 41.63

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.53 [0.70, 3.32] 2.9e-1 184
15 years 0.01 1.25 [0.67, 2.34] 4.8e-1 75
5 years 0.00 3.07 [1.81, 5.22] 3.3e-5 50
1 year 0.00 6.70 [3.67, 12.24] 5.8e-10 21

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_GAD – Generalized anxiety disorder
GWS hits: 1

Survival analyses between endpoints

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Plot

before Generalized anxiety disorder
after Generalized anxiety disorder

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Generalized anxiety disorder

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Endpoint not on priority list, no data to show.