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Recurrent or chronic depression

Endpoint Browser PheWeb

F5_DEPRESSION_RECURRENT

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions

not (F5_SCHIZO
or F5_SCHIZOAFF
or F5_BIPO

409530

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Check pre-conditions, main-only, mode, registry filters

Primary healthcare outpatient: ICD-10: F33
Hospital Discharge: ICD-10 F33
Cause of death: ICD-10 F33

3 out of 7 registries used, show all original rules.

20140

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Check minimum number of events None

20140

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Include endpoints None

20140

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Remove individuals based on genotype QC

19387

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F5_DEPRESSION_RECURRENT

Control definitions

Control exclude F5_PSYCH, ANTIDEPRESSANTS

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF10

Summary Statistics

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Key figures

All Female Male
Number of individuals 19387 14455 4932
Unadjusted prevalence (%) 4.71 6.28 2.71
Mean age at first event (years) 44.09 42.97 47.40

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.13 [3.22, 5.30] 4.3e-29 707
15 years 0.02 2.74 [2.24, 3.36] 3.2e-22 337
5 years 0.01 5.08 [4.14, 6.23] 7.5e-55 215
1 year 0.00 7.39 [5.43, 10.06] 5.7e-37 62

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_DEPRESSION_RECURRENT – Recurrent or chronic depression
GWS hits: 15

Survival analyses between endpoints

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Plot

before Recurrent or chronic depression
after Recurrent or chronic depression

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Recurrent or chronic depression

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Endpoint not on priority list, no data to show.