Unspecified dementia

F5_DEMNAS

obsolete_dementia: ['An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.']

Endpoint definition

FinnGen phenotype data

429209 individuals

diagram downward connector

Apply sex-specific rule None

429209

diagram downward connector

Check conditions None

429209

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F03
Hospital discharge: ICD-9 290|2941
Hospital discharge: ICD-8 2900|29019
Cause of death: ICD-10 F03
Cause of death: ICD-9 290|2941
Cause of death: ICD-8 2900|29019

2 out of 7 registries used, show all original rules.

4600

diagram downward connector

Check minimum number of events None

4600

diagram downward connector

Include endpoints None

4600

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

4408

diagram downward connector
F5_DEMNAS

Control definitions

Control exclude F5_ORGANIC

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3
Parent code in ICD-10 F00-F03
Name in latin Dementia non specificata

Summary Statistics

Key figures

All Female Male
Number of individuals 4408 1811 2597
Unadjusted prevalence (%) 1.07 0.79 1.43
Mean age at first event (years) 78.01 78.95 77.35

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.17 8.71 [7.67, 9.88] <1e-100 3148
15 years 0.02 2.33 [2.05, 2.63] 3.0e-40 741
5 years 0.01 6.23 [5.62, 6.91] <1e-100 1305
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: F5_DEMNAS – Unspecified dementia
GWS hits: 4

Survival analyses between endpoints

Plot

before Unspecified dementia
after Unspecified dementia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Unspecified dementia

Endpoint not on priority list, no data to show.