Anorexia (incl.atypical)

F5_ANOREX

anorexia nervosa: A disorder most often seen in adolescent females characterized by a refusal to maintain a minimally normal body weight, an intense fear of gaining weight, a disturbance in body image, and, in postmenarcheal females, the development of amenorrhea.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F50.0, F50.1
Hospital discharge: ICD-9 7830A|3071A
Hospital discharge: ICD-8 784
Cause of death: ICD-10 F50.0, F50.1
Cause of death: ICD-9 7830A|3071A
Cause of death: ICD-8 784

2 out of 7 registries used, show all original rules.

2198

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Check minimum number of events None

2198

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Include endpoints None

2198

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Remove individuals based on genotype QC

2115

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F5_ANOREX

Control definitions

Control exclude F5_BEHAVE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 2115 1668 447
Unadjusted prevalence (%) 0.51 0.72 0.25
Mean age at first event (years) 23.12 21.89 27.68

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.49 [1.74, 3.56] 6.7e-7 152
15 years 0.01 1.23 [0.86, 1.75] 2.5e-1 47
5 years 0.00 2.84 [1.93, 4.18] 1.3e-7 33
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: F5_ANOREX – Anorexia (incl.atypical)
GWS hits:

Survival analyses between endpoints

Plot

before Anorexia (incl.atypical)
after Anorexia (incl.atypical)

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Drugs most likely to be purchased after Anorexia (incl.atypical)

Endpoint not on priority list, no data to show.