Hypothyroidism due to medicaments and other exogenous substances

E4_HYTHYSUBS

hypothyroidism: Abnormally low levels of thyroid hormone.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E03.2#
Hospital discharge: ICD-9 2443
Cause of death: ICD-10 E03.2#
Cause of death: ICD-9 2443

2 out of 7 registries used, show all original rules.

289

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Check minimum number of events None

289

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Include endpoints None

289

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Remove individuals based on genotype QC

280

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E4_HYTHYSUBS

Control definitions

Control exclude E4_THYROID

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E03
Name in latin Hypothyreosis ex medicamentis sive aliis substantiis externis

Summary Statistics

Key figures

All Female Male
Number of individuals 280 202 78
Unadjusted prevalence (%) 0.07 0.09 0.04
Mean age at first event (years) 57.52 55.61 62.47

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_HYTHYSUBS – Hypothyroidism due to medicaments and other exogenous substances
GWS hits:

Survival analyses between endpoints

Plot

before Hypothyroidism due to medicaments and other exogenous substances
after Hypothyroidism due to medicaments and other exogenous substances

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Drugs most likely to be purchased after Hypothyroidism due to medicaments and other exogenous substances

Endpoint not on priority list, no data to show.