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Graves disease, strict definition

Endpoint Browser PheWeb

E4_GRAVES_STRICT

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions

GRAVES_COND
and not AMIODARONE

7068

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

3293

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Remove individuals based on genotype QC

3176

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E4_GRAVES_STRICT

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF7

No data for upset plot.

No data for upset table.

Summary Statistics

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Key figures

All Female Male
Number of individuals 3176 2689 487
Unadjusted prevalence (%) 0.77 1.17 0.27
Mean age at first event (years) 49.14 48.45 52.95

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.33 [2.25, 4.92] 1.7e-9 102
15 years 0.02 2.19 [1.49, 3.22] 7.5e-5 52
5 years 0.00 2.91 [1.83, 4.62] 5.9e-6 30
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_GRAVES_STRICT – Graves disease, strict definition
GWS hits: 14

Survival analyses between endpoints

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Plot

before Graves disease, strict definition
after Graves disease, strict definition

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Graves disease, strict definition

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Endpoint not on priority list, no data to show.