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Nontoxic single thyroid nodule

DOID EFO MESH SNOMED Endpoint Browser PheWeb

E4_GOITRENOD

nodular goiter: Goiter characterized by discrete tissue mass(es) that may or may not produce thyroid hormones.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E04.1
Hospital discharge: ICD-9 2410|2462
Cause of death: ICD-10 E04.1
Cause of death: ICD-9 2410|2462

2 out of 7 registries used, show all original rules.

2288

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Check minimum number of events None

2288

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Include endpoints None

2288

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Remove individuals based on genotype QC

2203

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E4_GOITRENOD

Control definitions

Control exclude E4_THYROID

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E04
Name in latin Struma atoxica uninodularis

Summary Statistics

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Key figures

All Female Male
Number of individuals 2203 1783 420
Unadjusted prevalence (%) 0.53 0.77 0.23
Mean age at first event (years) 50.78 49.21 57.46

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 0.90 [0.53, 1.54] 7.1e-1 121
15 years 0.00 0.59 [0.35, 1.01] 5.5e-2 44
5 years 0.00 1.44 [0.84, 2.48] 1.9e-1 28
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_GOITRENOD – Nontoxic single thyroid nodule
GWS hits: 2

Survival analyses between endpoints

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Plot

before Nontoxic single thyroid nodule
after Nontoxic single thyroid nodule

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Nontoxic single thyroid nodule

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Endpoint not on priority list, no data to show.