≡ Risteys
R10

Documentation Changelog GitHub Contact & Feedback

Other and/or unspecified nontoxic goitre

DOID EFO MESH SNOMED Endpoint Browser PheWeb

E4_GOITRENAS

goiter: Enlargement of the thyroid gland usually caused by lack of iodine in the diet, hyperthyroidism, or thyroid nodules. Symptoms include difficulty in breathing and swallowing.

Endpoint definition

↥
FinnGen phenotype data

429209 individuals

diagram downward connector

Apply sex-specific rule None

429209

diagram downward connector

Check conditions None

429209

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E04.8, E04.9
Hospital discharge: ICD-9 2419
Cause of death: ICD-10 E04.8, E04.9
Cause of death: ICD-9 2419

2 out of 7 registries used, show all original rules.

2632

diagram downward connector

Check minimum number of events None

2632

diagram downward connector

Include endpoints None

2632

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

2543

diagram downward connector
E4_GOITRENAS

Control definitions

Control exclude E4_THYROID

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 2543 2134 409
Unadjusted prevalence (%) 0.62 0.93 0.23
Mean age at first event (years) 54.39 53.17 60.80

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.43 [0.92, 2.23] 1.1e-1 213
15 years 0.01 0.96 [0.65, 1.43] 8.4e-1 82
5 years 0.00 2.11 [1.45, 3.07] 9.3e-5 54
1 year 0.00 4.15 [2.46, 6.98] 8.5e-8 19

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: E4_GOITRENAS – Other and/or unspecified nontoxic goitre
GWS hits: 16

Survival analyses between endpoints

↥

Plot

before Other and/or unspecified nontoxic goitre
after Other and/or unspecified nontoxic goitre

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and/or unspecified nontoxic goitre

↥

Endpoint not on priority list, no data to show.