Nontoxic diffuse goitre


No definition available.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E04.0
Hospital discharge: ICD-9 2400
Hospital discharge: ICD-8 240
Cause of death: ICD-10 E04.0
Cause of death: ICD-9 2400
Cause of death: ICD-8 240

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude E4_THYROID

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E04
Name in latin Struma atoxica diffusa

Summary Statistics

Key figures

All Female Male
Number of individuals 906 765 141
Unadjusted prevalence (%) 0.22 0.33 0.08
Mean age at first event (years) 50.85 49.76 56.72


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.53 [0.88, 2.64] 1.3e-1 81
15 years 0.01 1.22 [0.78, 1.91] 3.8e-1 37
5 years 0.00 1.98 [1.15, 3.42] 1.4e-2 18
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: E4_GOITREDIFF – Nontoxic diffuse goitre
GWS hits: 3

Survival analyses between endpoints


before Nontoxic diffuse goitre
after Nontoxic diffuse goitre

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Drugs most likely to be purchased after Nontoxic diffuse goitre

Endpoint not on priority list, no data to show.