Nontoxic diffuse goitre

DOID MESH Endpoint Browser PheWeb

E4_GOITREDIFF

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E04.0

Hospital discharge: ICD-9 2400

Hospital discharge: ICD-8 240

Cause of death: ICD-10 E04.0

Cause of death: ICD-9 2400

Cause of death: ICD-8 240

2 out of 7 registries used, show all original rules.

935

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Check minimum number of events None

935

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Include endpoints None

935

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Remove individuals based on genotype QC

906

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E4_GOITREDIFF

Control definitions

Control exclude E4_THYROID

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E04

Name in latin Struma atoxica diffusa

NAME	E4_GOITREDIFF
CONTROL_EXCLUDE	E4_THYROID
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	E040
HD_ICD_9	2400
HD_ICD_8	240
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	E040
COD_ICD_9	2400
COD_ICD_8	240
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Nontoxic diffuse goitre based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	906	765	141
Unadjusted prevalence (%)	0.22	0.33	0.08
Mean age at first event (years)	50.85	49.76	56.72

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	1.53 [0.88, 2.64]	1.3e-1	81
15 years	0.01	1.22 [0.78, 1.91]	3.8e-1	37
5 years	0.00	1.98 [1.15, 3.42]	1.4e-2	18
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_GOITREDIFF – Nontoxic diffuse goitre
GWS hits: 3

Survival analyses between endpoints

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Plot

before Nontoxic diffuse goitre
after Nontoxic diffuse goitre

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Table

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Drugs most likely to be purchased after Nontoxic diffuse goitre

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Endpoint not on priority list, no data to show.