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Other disorders of glucose regulation and pancreatic internal secretion

DOID MESH Endpoint Browser PheWeb

E4_GLUCOPANCREAS

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E15-E16
Cause of death: ICD-10 E15-E16

2 out of 7 registries used, show all original rules.

2472

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Check minimum number of events None

2472

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Include endpoints

2862

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Remove individuals based on genotype QC

2788

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E4_GLUCOPANCREAS

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other disorders of glucose regulation and pancreatic internal secretion based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

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Key figures

All Female Male
Number of individuals 2788 1332 1456
Unadjusted prevalence (%) 0.68 0.58 0.80
Mean age at first event (years) 48.01 43.60 52.05

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.13 6.63 [4.50, 9.77] 1.1e-21 657
15 years 0.02 2.64 [1.91, 3.65] 4.8e-9 194
5 years 0.01 7.30 [5.89, 9.04] 7.7e-74 237
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_GLUCOPANCREAS – Other disorders of glucose regulation and pancreatic internal secretion
GWS hits: 2

Survival analyses between endpoints

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Plot

before Other disorders of glucose regulation and pancreatic internal secretion
after Other disorders of glucose regulation and pancreatic internal secretion

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Drugs most likely to be purchased after Other disorders of glucose regulation and pancreatic internal secretion

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Endpoint not on priority list, no data to show.