Chronic myeloid leukaemia [CML], BCR/ABL-positive

DOID Endpoint Browser PheWeb

CML

No definition available.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 C92.1

Hospital discharge: ICD-9 2051

Cause of death: ICD-10 C92.1

Cause of death: ICD-9 2051

2 out of 7 registries used, show all original rules.

273

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Check minimum number of events None

273

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Include endpoints None

273

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Remove individuals based on genotype QC

258

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CML

Control definitions

Control exclude MYELOPROF

Extra metadata

First used in FinnGen datafreeze DF2, additional

NAME	CML
CONTROL_EXCLUDE	MYELOPROF
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	C921
HD_ICD_9	2051
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	C921
COD_ICD_9	2051
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Chronic myeloid leukaemia [CML], BCR/ABL-positive based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	258	123	135
Unadjusted prevalence (%)	0.06	0.05	0.07
Mean age at first event (years)	57.14	56.32	57.88

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CML – Chronic myeloid leukaemia [CML], BCR/ABL-positive
GWS hits:

Survival analyses between endpoints

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Plot

before Chronic myeloid leukaemia [CML], BCR/ABL-positive
after Chronic myeloid leukaemia [CML], BCR/ABL-positive

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Table

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Drugs most likely to be purchased after Chronic myeloid leukaemia [CML], BCR/ABL-positive

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Endpoint not on priority list, no data to show.