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Carcinoma in situ of breast, lobular

CD2_INSITU_BREAST_LOBULAR

breast ductal carcinoma in situ: A carcinoma entirely confined to the mammary ducts. It is also known as DCIS. There is no evidence of invasion of the basement membrane. Currently, it is classified into three categories: High-grade DCIS, intermediate-grade DCIS and low-grade DCIS. In this classification the DCIS grade is defined by a combination of nuclear grade, architectural growth pattern and presence of necrosis. The size of the lesion as well as the grade and the clearance margins play a major role in dictating the most appropriate therapy for DCIS.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule

Sex only females

239906

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Check conditions None

239906

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D05.0&
Cause of death: ICD-10 D05.0&

2 out of 7 registries used, show all original rules.

191

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Check minimum number of events None

191

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Include endpoints None

191

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Remove individuals based on genotype QC

184

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CD2_INSITU_BREAST_LOBULAR

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D05
Name in latin Carcinoma in situ lobulare mammae

Summary Statistics

Key figures

All Female Male
Number of individuals 184 184 -
Unadjusted prevalence (%) 0.04 0.08 -
Mean age at first event (years) 57.43 57.43 -

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: CD2_INSITU_BREAST_LOBULAR – Carcinoma in situ of breast, lobular
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Carcinoma in situ of breast, lobular

Endpoint not on priority list, no data to show.