Benign neoplasm: Sigmoid colon

CD2_BENIGN_SIGMOID_COLON

sigmoid neoplasm: Tumors or cancer of the sigmoid colon.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D12.5&
Hospital discharge: ICD-8 21136
Cause of death: ICD-10 D12.5&
Cause of death: ICD-8 21136

2 out of 7 registries used, show all original rules.

5565

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Check minimum number of events None

5565

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Include endpoints None

5565

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Remove individuals based on genotype QC

5382

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CD2_BENIGN_SIGMOID_COLON

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D12
Name in latin Neoplasma benignum coli sigmoidei

Similar endpoints

List of similar endpoints to Benign neoplasm: Sigmoid colon based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 5382 2557 2825
Unadjusted prevalence (%) 1.31 1.11 1.55
Mean age at first event (years) 64.42 63.12 65.60

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.20 [1.21, 4.02] 1.0e-2 788
15 years 0.01 1.54 [1.07, 2.23] 2.2e-2 355
5 years 0.00 3.14 [2.43, 4.08] 5.2e-18 272
1 year 0.00 5.09 [3.74, 6.93] 3.4e-25 93

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CD2_BENIGN_SIGMOID_COLON – Benign neoplasm: Sigmoid colon
GWS hits: 2

Survival analyses between endpoints

Plot

before Benign neoplasm: Sigmoid colon
after Benign neoplasm: Sigmoid colon

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Drugs most likely to be purchased after Benign neoplasm: Sigmoid colon

Endpoint not on priority list, no data to show.