Benign neoplasm: Rectum, anus and anal canal

CD2_BENIGN_RECTUM_ANAL

rectum cancer: A primary or metastatic malignant neoplasm that affects the rectum. Representative examples include carcinoma, lymphoma, and sarcoma.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

6150

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CD2_BENIGN_RECTUM_ANAL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Benign neoplasm: Rectum, anus and anal canal based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

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Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 6150 2913 3237
Unadjusted prevalence (%) 1.49 1.27 1.78
Mean age at first event (years) 63.40 61.51 65.11

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.40 [1.71, 3.37] 4.8e-7 904
15 years 0.01 1.39 [1.06, 1.82] 1.7e-2 416
5 years 0.00 2.45 [1.99, 3.02] 3.8e-17 271
1 year 0.00 4.38 [3.36, 5.71] 5.8e-28 94

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CD2_BENIGN_RECTUM_ANAL – Benign neoplasm: Rectum, anus and anal canal
GWS hits: 5

Survival analyses between endpoints

Plot

before Benign neoplasm: Rectum, anus and anal canal
after Benign neoplasm: Rectum, anus and anal canal

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Drugs most likely to be purchased after Benign neoplasm: Rectum, anus and anal canal

Endpoint not on priority list, no data to show.