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Benign neoplasm of bone and articular cartilage

DOID EFO MESH SNOMED Endpoint Browser PheWeb

CD2_BENIGN_BONE_CARTILAGE

chondrosarcoma: A malignant cartilaginous matrix-producing mesenchymal neoplasm arising from the bone and soft tissue. It usually affects middle-aged to elderly adults. The pelvic bones, ribs, shoulder girdle, and long bones are the most common sites of involvement. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D16
Cause of death: ICD-10 D16

2 out of 7 registries used, show all original rules.

1878

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Check minimum number of events None

1878

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Include endpoints

2717

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Remove individuals based on genotype QC

2629

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CD2_BENIGN_BONE_CARTILAGE

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D10-D36
Name in latin Neoplasma benignum ossis sive cartilaginis articularis

Similar endpoints

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List of similar endpoints to Benign neoplasm of bone and articular cartilage based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 2629 1567 1062
Unadjusted prevalence (%) 0.64 0.68 0.58
Mean age at first event (years) 39.49 38.90 40.36

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 0.72 [0.29, 1.79] 4.8e-1 194
15 years 0.00 0.62 [0.28, 1.36] 2.3e-1 74
5 years 0.00 1.25 [0.61, 2.56] 5.5e-1 34
1 year 0.00 2.85 [1.29, 6.30] 9.6e-3 14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_BENIGN_BONE_CARTILAGE – Benign neoplasm of bone and articular cartilage
GWS hits: 1

Survival analyses between endpoints

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Plot

before Benign neoplasm of bone and articular cartilage
after Benign neoplasm of bone and articular cartilage

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Drugs most likely to be purchased after Benign neoplasm of bone and articular cartilage

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Endpoint not on priority list, no data to show.