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Malignant melanoma of skin (controls excluding all cancers)

Endpoint Browser PheWeb

C3_MELANOMA_SKIN_EXALLC

No definition available.

Endpoint definition

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FinnGen phenotype data

individuals

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Apply sex-specific rule None

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Check conditions None

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Check pre-conditions, main-only, mode, registry filters

Cause of death: ICD-10 C43
Cause of death: ICD-9 172
Cause of death: ICD-8 172
Cancer registry: Topography ICD-O-3 C44
Cancer registry: Morphology ICD-O-3 8720|8721|8726|8730|8742|8743|8744|8745
Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints None

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Remove individuals based on genotype QC

3194

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C3_MELANOMA_SKIN_EXALLC

Control definitions

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

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Key figures

All Female Male
Number of individuals 3194 1542 1652
Unadjusted prevalence (%) 0.78 0.67 0.91
Mean age at first event (years) 59.80 56.02 63.32

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.08 [1.25, 3.46] 4.9e-3 564
15 years 0.01 0.93 [0.61, 1.42] 7.4e-1 165
5 years 0.01 3.54 [2.53, 4.97] 2.4e-13 208
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_MELANOMA_SKIN_EXALLC – Malignant melanoma of skin (controls excluding all cancers)
GWS hits: 11

Survival analyses between endpoints

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Plot

before Malignant melanoma of skin (controls excluding all cancers)
after Malignant melanoma of skin (controls excluding all cancers)

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Drugs most likely to be purchased after Malignant melanoma of skin (controls excluding all cancers)

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Endpoint not on priority list, no data to show.