This is a non-core endpoint: only basic statistics are computed.
See its core counterpart C3_GBM_EXALLC for full statistics.
Brain glioblastoma
DOID EFO MESH SNOMED Endpoint Browser
C3_GBM
brain glioblastoma: A WHO grade IV malignant astrocytic tumor that arises from the brain, usually the cerebral hemispheres. It is characterized by the presence of poorly differentiated astrocytes, cellular polymorphism, nuclear atypia, and increased mitotic activity. The prognosis is poor.
Endpoint definition
↥
FinnGen phenotype data
429209 individuals
Apply sex-specific rule None
429209
Check conditions
HLP_C3_GBM
273
Check pre-conditions, main-only, mode, registry filters
Cause of death: ICD-10
C71
Cause of death: ICD-9
191
Cause of death: ICD-8
191
Cancer registry: Topography ICD-O-3
C71
Cancer registry: Morphology ICD-O-3
9440
Cancer registry: Behaviour codes
3
2 out of 7 registries used, show all original rules.
273
Check minimum number of events None
273
Remove individuals based on genotype QC
253
C3_GBM
Control definitions
Control conditions
not HLP_C3_GBM
Extra metadata
Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF8
Show upset plot detailing case counts by codes
Or the full data table
Similar endpoints
↥List of similar endpoints to
Brain glioblastoma
based on the number of shared cases.
Broader endpoints:
- Brain glioblastoma (controls excluding all cancers)
- Brain glioblastoma and astrocytoma
- Brain glioblastoma and astrocytoma (controls excluding all cancers)
- Malignant neoplasm of brain (controls excluding all cancers)
- Malignant neoplasm of brain
Narrower endpoints:
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 253 | 95 | 158 |
| Unadjusted prevalence (%) | 0.06 | 0.04 | 0.09 |
| Mean age at first event (years) | 63.55 | 63.31 | 63.69 |
Mortality
Not a core endpoint, no data to show.
Age distribution of first events
Year distribution of first events
Cumulative Incidence
Not a core endpoint, no data to show.
Correlations
↥
Index endpoint: C3_GBM – Brain glioblastoma
GWS hits:
Survival analyses between endpoints
↥Plot
before Brain glioblastoma
after Brain glioblastoma
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Table
Loading survival analyses table