This is a non-core endpoint: only basic statistics are computed.
See its core counterpart C3_DLBCL_EXALLC for full statistics.
Diffuse large B-cell lymphoma
DOID EFO MESH Endpoint Browser
C3_DLBCL
diffuse large B-cell lymphoma: Diffuse large B-cell lymphoma is the most common subtype of non-Hodgkin lymphoma (NHL; see this term) in adults characterized by a median age of presentation in the sixth decade of life (but also rarely occurring in adolescents and children) with the initial presentation being single or multiple rapidly growing masses (that may or may not be painful) in nodal or extranodal sites (such as thyroid, skin, breast, gastrointestinal tract, testes, bone, or brain) and that can be accompanied by symptoms of fever, night sweats and weight loss. DLBCL has an aggressive disease course, with the elderly having a poorer prognosis than younger patients, and with relapses being common.
Endpoint definition
↥
FinnGen phenotype data
429209 individuals
Apply sex-specific rule None
429209
Check conditions
HLP_C3_DLBCL
1077
Check pre-conditions, main-only, mode, registry filters
Cause of death: ICD-10
C83.3
Cause of death: ICD-9
2000B
Cancer registry: Topography ICD-O-3
ANY
Cancer registry: Morphology ICD-O-3
9680
Cancer registry: Behaviour codes
3
2 out of 7 registries used, show all original rules.
1077
Check minimum number of events None
1077
Remove individuals based on genotype QC
1050
C3_DLBCL
Control definitions
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF8
Show upset plot detailing case counts by codes
Or the full data table
Similar endpoints
↥List of similar endpoints to
Diffuse large B-cell lymphoma
based on the number of shared cases.
Broader endpoints:
- Diffuse large B-cell lymphoma
- Diffuse large B-cell lymphoma (controls excluding all cancers)
- Any event in cancer register
- Malignant neoplasm (controls excluding all cancers)
- Malignant neoplasm
Narrower endpoints:
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1050 | 454 | 596 |
| Unadjusted prevalence (%) | 0.25 | 0.20 | 0.33 |
| Mean age at first event (years) | 65.59 | 63.61 | 67.10 |
Mortality
Not a core endpoint, no data to show.
Age distribution of first events
Year distribution of first events
Cumulative Incidence
Not a core endpoint, no data to show.
Correlations
↥
Index endpoint: C3_DLBCL – Diffuse large B-cell lymphoma
GWS hits:
Survival analyses between endpoints
↥Not a core endpoint, no data to show.
Drugs most likely to be purchased after Diffuse large B-cell lymphoma
↥Endpoint not on priority list, no data to show.