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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_DLBCL_EXALLC for full statistics.

Diffuse large B-cell lymphoma

C3_DLBCL

diffuse large B-cell lymphoma: Diffuse large B-cell lymphoma is the most common subtype of non-Hodgkin lymphoma (NHL; see this term) in adults characterized by a median age of presentation in the sixth decade of life (but also rarely occurring in adolescents and children) with the initial presentation being single or multiple rapidly growing masses (that may or may not be painful) in nodal or extranodal sites (such as thyroid, skin, breast, gastrointestinal tract, testes, bone, or brain) and that can be accompanied by symptoms of fever, night sweats and weight loss. DLBCL has an aggressive disease course, with the elderly having a poorer prognosis than younger patients, and with relapses being common.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions

HLP_C3_DLBCL

1077

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Check pre-conditions, main-only, mode, registry filters

Cause of death: ICD-10 C83.3
Cause of death: ICD-9 2000B
Cancer registry: Topography ICD-O-3 ANY
Cancer registry: Morphology ICD-O-3 9680
Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

1077

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Check minimum number of events None

1077

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Include endpoints

1077

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Remove individuals based on genotype QC

1050

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C3_DLBCL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF8

Summary Statistics

Key figures

All Female Male
Number of individuals 1050 454 596
Unadjusted prevalence (%) 0.25 0.20 0.33
Mean age at first event (years) 65.59 63.61 67.10

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: C3_DLBCL – Diffuse large B-cell lymphoma
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Diffuse large B-cell lymphoma

Endpoint not on priority list, no data to show.