Chronic lymphocytic leukaemia (controls excluding all cancers)

C3_CLL_EXALLC

No definition available.

Endpoint definition

FinnGen phenotype data

individuals

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Apply sex-specific rule None

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Check conditions

HLP_C3_CLL

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Check pre-conditions, main-only, mode, registry filters

Cause of death: ICD-10 C91.1
Cause of death: ICD-9 2041A
Cause of death: ICD-8 20415
Cancer registry: Topography ICD-O-3 ANY
Cancer registry: Morphology ICD-O-3 9823
Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints

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Remove individuals based on genotype QC

668

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C3_CLL_EXALLC

Control definitions

Control exclude C3_CANCER, C3_CANCER_WIDE
Control conditions not HLP_C3_CLL

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF8

Summary Statistics

Key figures

All Female Male
Number of individuals 668 208 460
Unadjusted prevalence (%) 0.16 0.09 0.25
Mean age at first event (years) 67.08 66.05 67.54

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.12 5.97 [3.51, 10.15] 4.5e-11 234
15 years 0.02 2.98 [2.07, 4.29] 4.1e-9 94
5 years 0.01 4.78 [3.45, 6.62] 4.5e-21 74
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: C3_CLL_EXALLC – Chronic lymphocytic leukaemia (controls excluding all cancers)
GWS hits: 5

Survival analyses between endpoints

Plot

before Chronic lymphocytic leukaemia (controls excluding all cancers)
after Chronic lymphocytic leukaemia (controls excluding all cancers)

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Drugs most likely to be purchased after Chronic lymphocytic leukaemia (controls excluding all cancers)

Endpoint not on priority list, no data to show.