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Malignant neoplasm of breast, HER-negative (controls excluding all cancers)

Endpoint Browser PheWeb

C3_BREAST_ERNEG_EXALLC

No definition available.

Endpoint definition

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FinnGen phenotype data

individuals

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Apply sex-specific rule

Sex only females

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Check conditions

not RX_ERPLUS

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Check pre-conditions, main-only, mode, registry filters

Cause of death: ICD-10 C50
Cause of death: ICD-9 174
Cause of death: ICD-8 174
Cancer registry: Topography ICD-O-3 C50
Cancer registry: Morphology ICD-O-3 ANY
Cancer registry: Behaviour codes [23]

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints None

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Remove individuals based on genotype QC

6188

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C3_BREAST_ERNEG_EXALLC

Control definitions

Control exclude C3_CANCER, C3_CANCER_WIDE
Control conditions not RX_ERPLUS

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF9

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No upset table: script not run.

Summary Statistics

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Key figures

All Female Male
Number of individuals 6188 6188 -
Unadjusted prevalence (%) 1.50 2.69 -
Mean age at first event (years) 57.58 57.58 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.49 [1.16, 1.92] 1.8e-3 915
15 years 0.01 0.88 [0.72, 1.07] 2.1e-1 317
5 years 0.00 2.21 [1.82, 2.68] 8.3e-16 260
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_BREAST_ERNEG_EXALLC – Malignant neoplasm of breast, HER-negative (controls excluding all cancers)
GWS hits: 13

Survival analyses between endpoints

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Plot

before Malignant neoplasm of breast, HER-negative (controls excluding all cancers)
after Malignant neoplasm of breast, HER-negative (controls excluding all cancers)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Malignant neoplasm of breast, HER-negative (controls excluding all cancers)

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Endpoint not on priority list, no data to show.