Other specified/unspecified bacterial intestinal infections

BACT_INTEST_INFECTION_NOS

dysentery: Acute inflammation of the intestine associated with infectious diarrhea of various etiologies, generally acquired by eating contaminated food containing toxins, biological derived from bacteria or other microorganisms. Dysentery is characterized initially by watery feces then by bloody mucoid stools. It is often associated with abdominal pain; fever; and dehydration.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 A04.8, A04.9
Hospital discharge: ICD-9 0085X
Hospital discharge: ICD-8 008[2-3]
Cause of death: ICD-10 A04.8, A04.9
Cause of death: ICD-9 0085X
Cause of death: ICD-8 008[2-3]

2 out of 7 registries used, show all original rules.

2041

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Check minimum number of events None

2041

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Include endpoints None

2041

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Remove individuals based on genotype QC

1913

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BACT_INTEST_INFECTION_NOS

Control definitions

Control exclude IBD_BACT_INTEST_INFECTIONS

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1913 1105 808
Unadjusted prevalence (%) 0.46 0.48 0.44
Mean age at first event (years) 55.10 53.20 57.69

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.01 [2.87, 5.62] 6.3e-16 296
15 years 0.02 2.20 [1.66, 2.91] 4.4e-8 123
5 years 0.01 4.12 [3.06, 5.56] 1.3e-20 81
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: BACT_INTEST_INFECTION_NOS – Other specified/unspecified bacterial intestinal infections
GWS hits:

Survival analyses between endpoints

Plot

before Other specified/unspecified bacterial intestinal infections
after Other specified/unspecified bacterial intestinal infections

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Drugs most likely to be purchased after Other specified/unspecified bacterial intestinal infections

Endpoint not on priority list, no data to show.