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Acute alcohol intoxication

DOID EFO MESH SNOMED Endpoint Browser PheWeb

ALCOHOLACUTE10

Hepatitis, Alcoholic: INFLAMMATION of the LIVER due to ALCOHOL ABUSE. It is characterized by NECROSIS of HEPATOCYTES, infiltration by NEUTROPHILS, and deposit of MALLORY BODIES. Depending on its severity, the inflammatory lesion may be reversible or progress to LIVER CIRRHOSIS.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F10.0
Cause of death: ICD-10 F10.0

2 out of 7 registries used, show all original rules.

7213

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Check minimum number of events None

7213

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Include endpoints None

7213

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Remove individuals based on genotype QC

7000

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ALCOHOLACUTE10

Control definitions

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 F10

Summary Statistics

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Key figures

All Female Male
Number of individuals 7000 2508 4492
Unadjusted prevalence (%) 1.70 1.09 2.47
Mean age at first event (years) 48.89 42.27 52.58

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.19 10.34 [5.64, 18.96] 4.1e-14 1519
15 years 0.03 3.77 [2.42, 5.85] 3.7e-9 359
5 years 0.01 8.34 [6.09, 11.42] 5.7e-40 309
1 year 0.02 92.29 [70.63, 120.59] <1e-100 777

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ALCOHOLACUTE10 – Acute alcohol intoxication
GWS hits: 1

Survival analyses between endpoints

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Plot

before Acute alcohol intoxication
after Acute alcohol intoxication

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acute alcohol intoxication

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Endpoint not on priority list, no data to show.