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Other spirochaetal diseases

DOID EFO MESH Endpoint Browser PheWeb

AB1_OTHER_SPIROCHAETAL

Pinta: An infectious disease of the skin caused by Treponema carateum that occurs only in the western hemisphere. Age of onset is between 10 and 20 years of age. This condition is characterized by marked changes in the skin color and is believed to be transmitted by direct person-to-person contact.

Endpoint definition

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FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 A65-A69
Hospital discharge: ICD-9 104|08[7-7]
Hospital discharge: ICD-8 08[8-9]
Cause of death: ICD-10 A65-A69
Cause of death: ICD-9 104|08[7-7]
Cause of death: ICD-8 08[8-9]

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints

2595

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Remove individuals based on genotype QC

2492

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AB1_OTHER_SPIROCHAETAL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 2492 1508 984
Unadjusted prevalence (%) 0.60 0.65 0.54
Mean age at first event (years) 55.49 53.55 58.47

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.84 [0.99, 3.40] 5.2e-2 125
15 years 0.01 1.19 [0.70, 2.02] 5.1e-1 62
5 years 0.00 1.36 [0.78, 2.40] 2.8e-1 28
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: AB1_OTHER_SPIROCHAETAL – Other spirochaetal diseases
GWS hits: 2

Survival analyses between endpoints

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Plot

before Other spirochaetal diseases
after Other spirochaetal diseases

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Drugs most likely to be purchased after Other spirochaetal diseases

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Endpoint not on priority list, no data to show.